Retinoids Help Normalize KeratinizationAlthough the mechanism by which topical and systemic retinoids help restore acne follicles to a healthy state is unknown, it has been well demonstrated that they normalize keratinization within the infundibular region of the follicle, so that shed follicular cells slough to the surface of the skin rather than clump together and obstruct the pores.After exposure to retinoids, follicular cells actually turn over more rapidly than they would in a pre-acne state.Retinoic acid has a high affinity for the gamma retinoid receptors, which are believed to be integral to the pathogenesis of acne.In addition to their ability to reverse abnormal keratinization within the follicle, the topical retinoids - especially adapalene (Differin®), a naphthoic acid derivative - may have anti-inflammatory properties and thus may address two factors involved in the development of acne.
But if you suffer from severe acne and nothing seems to work, then see a dermatologist. Sometimes prescribed medication will be needed to get the severity of the acne under better control.
Do you know people shop online to obtain accutane without a prescription? Without first at least consulting with a doctor?...Taking accutane unsupervised? Do you think that's a good idea? That's a scary thought to me. First of all, make sure you know all the side-effects involved when taking certain drugs for acne.
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tags: natural acne scar removal, can we reduce acne scars with chemical peels, foods i should eat if i have acne
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